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mbox is fine till it corrupts, then you get to play with a 7bit ascii text file with a multitude of encoded attachments...
i have a macro for ultraedit to rebuild them as some of the more popular anti virus products have a ball corrupting or deleting them and we get people in wanting us to help them recover some long lost super important email. i just love the backup lecture... some learn, some dont :p
best thing about thunderbird is it copes well with opening outlook express data that neither of the outlook programs will cope with at times....
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No contest - Tbird, say no to micro shaft and yes to open source :p.
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unless you need to calendar, notes, tasks etc in outlook, go for outlook express, it's free and has a smaller footprint.
As far as either outlook or thunderbird crashing and burning well if you don't have a back up, more fool you. ;)