ABS is a fail safe system, pull the power to the block and you get normal brakes. That means that the paths from MC to each caliper is open.
Thinking on the fly, for the ABS function typically the valve for the locked wheel is closed (and vented?) to stop it from locking, carried out on a per wheel basis, the idea being is automated cadence braking on each wheel, with pressure supplied by you/pump. ABS mode.
ETC is the pump supplying braking to a wheel, so I guess if you want to brake FR you close FL,RR,RL valves and engage pump.
HDC is probably more like ABS with the pump replacing your foot.
I'm thinking from that to bleed the block you want to operate the pump to bleed the pump body and relief. If everything is open then I guess relief area may not get it, unless on over pressure.
FWIW, I've actually bled the block itself with a contraption to control all the valves and pump, but that was very specifically done to clean power steering out. Back on the car I used the relay bypass to bleed and didn't find any issues what so ever.
Other times I've used the relay bypass and nanocom to bleed, and again the pedal has been great afterwards.

