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Ive always done it laying down with my head tilted back and towards the eye I want to put the drops into.
lets say I want to put drops into the left eye
I turn my head left, I hold the eye open with my left hand and rest the thumb joint of my right hand on my right eye. This positions the bottle right over my left eye and I just look up at the bottle and let the drops fall.
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May not be quite as efficient, but can be done with your eyes closed.
While laying flat Aim the bottle at the tear duct (next to your nose) and drop the two drops in with the eye closed, lean away and open your eye and it will usually drain into your tear duct and into the eye.
Works for the kids, then they get 2 drops at once, and can prepare themselves.
