Originally Posted by
prelude
lightly apply a second coat and start scrubbing it off to see if you can get the residue off. Depending on what you want to do with the panel, fill it or paint in straight away you should use different grits of sandpaper. If you are going to apply primer, you can get away with 180. Sand down the primer with 240 and then apply the final coats of paint. If you want a really smooth finish you could use 500 in between layers but that is a lot of work and will get you a finish like a show car.
As a rule of thumb: remember that the scratches that the sandpaper makes need to be filled with paint and you can actually see the sanding through the paint if you use to course a sandpaper. Primer is usually slightly thicker and thus can fill the 180 scratches just fine, top coats need finer paper like 240. Also, do not sand in one direction, make circles or cross stroke.
Cheers,
-P