The typical 110 long range tank that takes the normal station wagon tank position, and has a wing section that extends up under the rear quarter panel, won't fit. As you surmised, the chassis is wider there, and thus the cut out for the chassis will be in the wrong spot. But a standard station wagon tank, at ~70l capacity, will double your range! Best check the fuel tank mounts, chances are the rear crossmember mounts won't be there, not sure about the other crossmember mounts.
The Isuzu doesn't need an in-tank fuel pump which will simplify matters a lot.

