Yeah, sure can. For several years now, our '97 300Tdi Discovery has had an electric vacuum pump.
When the mechanical pump failed and was removed, I found the pump cam was quite pitted and decided it wasn't a good idea to run a new pump against it.
The pump I'm using is from a Volvo 740 Turbo. It includes a vacuum switch and starts at about 15" Hg and stops at 20-21" Hg. However, these don't last forever either - I'm on my second one since 2008.
My local mechanic who's qualified to issue Modification Plates in Qld looked up his book and couldn't find any need for certification of a vacuum pump change (unlike, say, changing from drums to discs etc.)
You will need to make a blanking plate to cover the hole in the block.
Pics below.

