I went to the old MS paid antimalware years ago, very happy when it morphed into the free MSE. Compared to the resource hungry Norton software it is far superior.
I think, however, people are missing a key strategy for preventing malware infections. Use a log on with diminished privileges! Create an admin log on for installing software and other maintenance, and turn all other user accounts into non-administrator.
The UAC is much maligned, disable it if you must while setting up a new PC but reinstate it once done.
These two strategies will add to your system security. Malware can only install itself using the admin rights of the current user, if the current user cannot install software, the malware can't install. And, annoying as the UAC is (particularly in Vista) having something jump up if system changes are made is a good thing.
And, don't install multiple anti-malware programs. Pick one and stay with it. If you don't like it, remove it completely (using the remoavl tools from the vendors website) and install another.
Make sure you check for updates on a regular basis, and run scheduled scans. This is where programs like MSE come into their own, try using a computer when Norton, McAfee, etc are scanning. Small footprint programs are the way to go!





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