Yes.
Funnily enough I have a spreadsheet setup just for that on the 4BD1T.:cool:
But the basics are quite simple, the big turbo must be capable of passing the total air consumption you expect, the small turbo must be capable of working alone as a single turbo.
My compound turbo setup is on hold until I can add more weight to the flywheel. I already have more torque than I can smoothly use below 2000rpm. More boost down low won't help me at all. In fact I'm about to swap a larger turbine housing onto my T25 to swap some low end boost for some better high rpm (like 3000rpm) flow.

