I recently had the same in my 101 but as it has tubes I knew the screw was in the tread only as the tyre was still full of air.
I also had one in a tubeless tyre a while back and had the same dilemma. I ultimately decided that there was always a chance the tyre would deflate at high speed and possibly cause an accident.
I think that while the risk is low of a failure with the screw in, it is still a possibility and as such the risk is too great.
Take the tyre in to get the screw removed and the tyre properly repaired. Resist the urge to remove it yourself and repair as the repairs you can do yourself are meant to be temporary though I do have one in my spare tyre that has been there for a few years.
Garry
REMLR 243
2007 Range Rover Sport TDV6
1977 FC 101
1976 Jaguar XJ12C
1973 Haflinger AP700
1971 Jaguar V12 E-Type Series 3 Roadster
1957 Series 1 88"
1957 Series 1 88" Station Wagon
Bookmarks