Thread: Random Question. What are your thoughts on Cannabis?

Originally Posted by POD

I'm astonished at the statement earlier in this thread that 'no had has ever died from smoking marijuana'. Validating this statement would require investigating the cause of every death that has ever occurred.
Might I also add that no-one has ever died from jumping off a tall building. Jumping off tall buildings appears to me to be a harmless, exhilarating thing to do. I am aware, however, that there is a strong statistical association between jumping from tall buildings and landing heavily on pavement a short time later. This tells me that regardless of how much fun jumping off buildings may appear to be, only a complete fool would get involved in it.
That is pretty much how I feel about marijuana.

I understand where you are coming from but that is a ridiculous analogy.

Translated from:Le cannabis nuit gravement à la mémoire - Le Point

Not only this drug has adverse effects on the ability to perform common tasks, but it is also an endocrine disruptor.

Working memory allows for daily operations (reflection, reading, writing, arithmetic ...) on the information stored temporarily (a few seconds to minutes). This ability is responsible for the integration of audio information, visual and spatial. Unfortunately, cannabis use has a deleterious effect on the memory. The team of Giovanni Marsicano (Inserm U862 in Bordeaux in collaboration with that of Xia Zhang, Ottawa, Canada) is to determine the precise causes, for the first time. This work is published in the journal Cell dated March 2, 2012

"Cannabis use causes disturbances that prevent the consumer to perform tasks that he knows, however, make every day," said Giovanni Marsicano. Because there are cannabinoid receptors (compounds present in leaf and flower cannabis) on certain cells of the hippocampus, a brain structure essential for the coordination and modulation of memories. Beware, it's not neurons, but other cells called glia, which represent about half the brain volume and that provide support, nutrition of neurons and the formation of the myelin sheath that insulates nerves .

Declining fertility

The researchers described in mice, one mechanism by which cannabis causes deleterious effects on working memory: once bound to its receptors, it decreases the strength of connections between neurons in the hippocampus. A message that should get across to teenagers ... Still, the team of Giovanni Marsicano from his work a rather positive conclusion when cannabis is used in a therapeutic setting. After recalling the interest of cannabis in the treatment of several diseases, the researchers estimate that "the description of the specific mechanisms of action of cannabinoids in the hippocampus will maximize their potential for therapeutic use, today limited by significant side effects associated with their use. "

That consumers of joints do not rejoice too soon, as experts, met earlier this week in the National Assembly at the initiative of several members, stressed that cannabis is an endocrine disruptor, in the same way as molecules such as bisphenol A, phthalates, parabens, and has the same inhibitory effects on sexual function in men. By acting on all hormonal systems, it is believed to generate a decline in male fertility, cause birth defects and even contribute to obesity or diabetes. In other words, smoking joints regularly, it does nothing trivial!