Ivermectin has been shown to inhibit reproduction of the virus in vitro. " Specifically, ivermectin appeared to block critical intracellular transport proteins that SARS-CoV-2 uses to invade human cells. The drug may also interfere with the virus' ability to latch onto human cells with its spike protein".
Unfortunately, the concentration required to do this is at least 100 times the level that is approved for use in humans. Now the authorities have no doubt put a good safety margin on that allowable level - but 100 fold?
It is not surprising that "the petri dish data has yet to translate into any convincing clinical data that the drug is actually useful against COVID-19 in whole people. Studies in humans have been small and produced inconsistent results. Meta-analyses aimed at weeding out potential clinical benefits have struggled with faulty data, and some have been
retracted".
In other words, researchers have either used doses so low that they have no discernible effect, or gone a bit higher and lost too many patients!
Pharmaceutical research is littered with compounds that work in vitro but either not in patients or not without killing them!
John
JDNSW
1986 110 County 3.9 diesel
1970 2a 109 2.25 petrol
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